Genetic heterogeneity of autoimmune disorders in the nonobese diabetic mouse |
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Authors: | Johansson A C M Lindqvist A-K B Johannesson M Holmdahl R |
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Affiliation: | Section for Medical Inflammation Research, Department of Cell and Molecular Biology, University of Lund, Sweden. asa.johansson@inflam.lu.se |
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Abstract: | The nonobese diabetic mouse is highly susceptible not only to diabetes but to several autoimmune diseases, and one might suspect that these are controlled by a shared set of genes. However, based on various gene-segregation experiments, it seems that only a few loci are shared and that each disorder is influenced also by a unique set of genes. |
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