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Humoral immune response to an allogenic foetus in normal fertile women and recurrent aborters
Authors:Suraksha?Agrawal  author-information"  >  author-information__contact u-icon-before"  >  mailto:suraksha@sgpgi.ac.in"   title="  suraksha@sgpgi.ac.in"   itemprop="  email"   data-track="  click"   data-track-action="  Email author"   data-track-label="  "  >Email author,Manoj?K?Pandey,SK?Mandal,LC?Mishra,SS?Agarwal
Affiliation:(1) Department of Medical Genetics, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, 226014, U.P., India;(2) Biometry and Statistics Division, Central Drug Research Institute, Post Box 173, 226001 Lucknow, U.P., India;(3) Institute of Life Sciences, Chhatrapati Sahu Ji Maharaj University, Kanpur, 208024, U.P., India
Abstract:

Background  

Several humoral immune factors are responsible for a successful pregnancy. There are a few studies, which demonstrate the role of antipaternal cytotoxic antibodies (APCA) and mixed lymphocyte reaction blocking factor (MLR-Bf) in the maintenance of pregnancy. However, these factors have not been studied in women with history of recurrent spontaneous abortion (RSA). We designed this study to review the role of APCA and MLR-Bf in normal pregnancy as well as in women with a history of RSA.
Keywords:
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