扩大蝶窦入路显微手术切除巨大侵袭性垂体瘤

目的 探讨扩大蝶窦入路显微手术切除巨大侵袭性垂体瘤的方法和治疗效果。方法 本组11例，平均病程4．8年；肿瘤最大径4．0cm-6．3cm；海绵窦均有侵袭，其中单侧侵袭8例，双侧受累3例；4例肿瘤包绕颈内动脉，累及斜坡2例。本组均采用扩大蝶窦入路显微手术切除术切除巨大侵袭性垂体瘤。结果 肿瘤生切除2例，次全切除6例，大部切除3例。结论 扩大经蝶入路。术野显露较大，肿瘤暴露优于传统经蝶入路。充分利用海绵窦静脉丛已大部分乃至完全闭塞的解剖特点。切开海绵窦。最大限度的切除肿瘤。

Microsurgical treatment of giant invasive pituitary adenoma through extensive transsphenoidal approach

Objective To explore the method and therapeutic effect of microsurgical treatment of giant invasive pituitary adenoma through extensive transsphenoidal approach. Methods The clinical data of 11 patients with giant invasive pituitary adenoma treated by extensive transsphenoidal approach were analyzed retrospectively. In all of the 11 patients, pituitary adenoma were larger than 4 em in diameter, invading the eavemons sinus, including 8 unilateral invasion to the eavemons sinus, 3 bilateral invasion 4 wrapped internal carotid artery , 2 including elivus. Results Of 11 eases, tumors of 2 were totally reseeted and 6 subtotally. Conclusion Extensive transsphenoidal approach has prominent benefit on microsurgical treatment of giant invasive pituitary adenoma by amply exposing operational area ,and split the occlusive eavemons sinus .