| 血吸虫病疫苗联合免疫的研究进展 |
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| 引用本文： | 胡媛,石佑恩.血吸虫病疫苗联合免疫的研究进展[J].国际医学寄生虫病杂志,2006,33(1):28-31. |
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| 作者姓名： | 胡媛 石佑恩 |
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| 作者单位： | 430030,武汉,华中科技大学同济医学院病原生物系 |
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| 摘 要： | 血吸虫病疫苗是减轻血吸虫感染、控制血吸虫病传播的重要措施。为提高血吸虫病疫苗的免疫效果,国内外通过不同抗原基因的连接、不同疫苗抗原的组合或从噬菌体肽库中筛选到若干个不同抗原表位的混合等途径来实现复合疫苗或多种单一疫苗的联合免疫,并取得较好的成果。
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| 关 键 词： | 血吸虫病 多价疫苗 联合免疫 |
| 修稿时间： | 2005年8月30日 |
Progress of combined immunization with schistosomiasis vaccines |
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| HU Yuan,SHI You-en.Progress of combined immunization with schistosomiasis vaccines[J].International JOurnal of Medical Parasitic Diseases,2006,33(1):28-31. |
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| Authors: | HU Yuan SHI You-en |
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| Abstract: | Schistosomiasis vaccine is an important long-term strategy in the control of infection and transmission of Schistosoma. Improving vaccine efficacy against schistosomiasis can be achieved by: multivalent vaccines or cocktail univalent vaccine. Combined immunization was realized by connection with different antigen sequences, combination with different antigen proteins or mixing different epitopes that were screened from the phage peptide library. Progress has been made towards development of vaccines against schistosomiasis with effective protection and long-lasting immunity. |
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| Keywords: | Schistosomiasis Multivalent vaccines Combined immunization |
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