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胸水、血清中CEA、NSE、CYFRA21-1对恶性胸腔积液的诊断价值
引用本文:张晶,刘国辉,谢舒枝,曾剑峰.胸水、血清中CEA、NSE、CYFRA21-1对恶性胸腔积液的诊断价值[J].临床肺科杂志,2009,14(4):482-484.
作者姓名:张晶  刘国辉  谢舒枝  曾剑峰
作者单位:深圳市东湖医院,518000
摘    要:目的探讨胸水、血清中CEA、NSE、CYFRA21-1对恶性胸腔积液的诊断价值。方法测定40例恶性胸水和40例非恶性胸水及其血清中CEA、NSE、CYFRA21—1的水平。结果恶性胸水组胸水及其血清中CEA、NSE、CYFRA21-1的水平明显高于非恶性胸水组,有显著性差异(P〈0.05)。恶性胸水组3项联合检测的阳性率明显高于单项检测(P〈0.05)。结论联合检测胸水及其血清中CEA、NSE、CYFRA21-1对鉴别良、恶性胸水有一定的临床价值。

关 键 词:癌胚抗原(CEA)  神经元特异性烯醇化酶(NSE)  细胞角蛋白(CYFRA21—1)  胸腔积液

Value of CEA,NSE,CYFRA21-1 in pleural fluid and serum for the diagnosis of malignant pleural exudates
ZHANG Jing,LIU Guo-hui,XIE Shu-zhi,ZENG Jian-feng.Value of CEA,NSE,CYFRA21-1 in pleural fluid and serum for the diagnosis of malignant pleural exudates[J].Journal of Clinical Pulmonary Medicine,2009,14(4):482-484.
Authors:ZHANG Jing  LIU Guo-hui  XIE Shu-zhi  ZENG Jian-feng
Institution:ZNANG Jing,LIU Guo-hui,XIE Shu-zhi,ZENG Jian-feng Donghu Hospital of Shenzhen City,Shenzhen 518000,China,WU Fu-cheng.The First People's Hospital of Shenzhen City
Abstract:Objective To explore the diagnostic value of malignant pleural exudates of carcinoembryonic antigen (CEA), neuron specific enolase (NSE), and cytokeratin 19 fragments (CYFRA21-1) in pleural fluid and serum.Methods Measures were made and analyzed of CEA, NSE, CYFRA21-1 in pleural fluid and serum of 80 cases of pleural exudates patients.Results Values of CEA, NSE, CYFRA21-1 in pleural fluid and serum concentration in malignant pleural exudates was significantly higher than those in tuberculous pleural exudate...
Keywords:carcinoembryonic antigen(CEA)  neuron specific enolase (NSE)  cytokeratin 19 fragments (CYFRA21-1)  pleural exudates
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