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中医药对类风湿关节炎细胞凋亡及基因表达谱的影响
引用本文:刘喜德,张金禄,叶丽红,陈滢,刘风云.中医药对类风湿关节炎细胞凋亡及基因表达谱的影响[J].中华中医药杂志,2010(4).
作者姓名:刘喜德  张金禄  叶丽红  陈滢  刘风云
作者单位:浙江省中西医结合医院关节病科;浙江中医药大学;
基金项目:浙江省中医药科技计划项目(No.2007CB195,2008CA086);;杭州市医药卫生科技计划项目(No.2007B0034)~~
摘    要:类风湿关节炎(rheumatoid arthritis,RA)是一病因未明、致残性、全身性自身免疫性疾病。文章从中药提取物、中药复方对RA细胞凋亡的影响,RA基因表达谱差异、基因表达谱应用于RA证的研究及中药复方对RA基因表达谱影响等几方面研究进展加以综合和分析,旨在为RA的治疗及深化研究提供科学的理论依据。

关 键 词:类风湿关节炎  中医药  细胞凋亡  基因表达  综述  

Effects of TCM on gene expression profiles and apoptosis of RA
LIU Xi-de,ZHANG Jin-lu,YE Li-hong,CHEN Ying,LIU Feng-yun.Effects of TCM on gene expression profiles and apoptosis of RA[J].China Journal of Traditional Chinese Medicine and Pharmacy,2010(4).
Authors:LIU Xi-de  ZHANG Jin-lu  YE Li-hong  CHEN Ying  LIU Feng-yun
Institution:1Department of Arthropathy;Integrated Traditional and Western Medicine Hospital of Zhejiang Province;Hangzhou 310003;China;2Zhejiang Chinese Medical University;Hangzhou 310053;China
Abstract:Rheumatoid Arthritis (RA) is a systemic self-immune disease with unclear etiopathogenisis and high frequency of disability. Through synthesizing and analyzing research development of RA including the effects of Traditional Chinese Medicine (TCM) on the gene expression profiles and apoptosis, the differential gene expression, application of gene expression profiles in RA research, this article intend to provide scientific theoretical basement for treatment and deep research of RA.
Keywords:RA  TCM  Apoptosis  Gene expression profi les  Rview  
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