| 人子宫内膜腺上皮核仁管状系统的研究现状 |
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| 引用本文： | 冀立娟,张雷,王蔼明. 人子宫内膜腺上皮核仁管状系统的研究现状[J]. 生殖医学杂志, 2009, 18(3): 312-316. DOI: 10.3969/j.issn.1004-3845.2009.03.040 |
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| 作者姓名： | 冀立娟 张雷 王蔼明 |
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| 作者单位： | 1. 中国人民解放军海军总医院妇产科,北京,100037
2. 河北医科大学组织胚胎学教研室,河北石家庄,050017 |
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| 基金项目： | 全军医学科学技术研究"十一五"计划 |
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| 摘 要： | 排卵后的子宫内膜发生程序性变化，开始具备接受胚胎的能力，此过程中内膜上皮细胞超微形态出现了显著的变化。核仁管状系统是在透射电镜下观察到的子宫内膜腺上皮细胞核内的特殊结构，其形成与核仁蛋白Nopp140有关，其出现是子宫内膜容受性的重要标志。本文拟从整体上对核仁管状系统的形态、功能及其与子宫内膜容受性和Nopp140的关系进行综述。
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| 关 键 词： | 子宫内膜腺上皮 核仁管状系统 透射电镜 Nopp140 子宫内膜容受性 |
Current study of nucleolar channel system in human endometrial glandular epithelium |
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| JI Li-juan,ZHANG Lei,WANG Ai-ming. Current study of nucleolar channel system in human endometrial glandular epithelium[J]. Journal of Reproductive Medicine, 2009, 18(3): 312-316. DOI: 10.3969/j.issn.1004-3845.2009.03.040 |
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| Authors: | JI Li-juan ZHANG Lei WANG Ai-ming |
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| Affiliation: | JI Li-juan , ZHANG Lei , WANG Ai-ming( 1. Department of Obstetrics ＆ Gynecology, Navy General Hospital, Beijing 100037; 2. Department of Histology ＆ Embryology, Hebei Medical University, Shijiazhuang 050031) |
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| Abstract: | After ovulation, the proceeding changes are happened in human endometrial glandular epithelium. The ultrastructures of the endometrium have noticeable changes, which is getting ready to accept the embryo. Nucleolar channel system （NCS） is a special intranuclear structure of human endometrial glandular epithelium, which can be observed by transmission electron microscope （TEM）. Its formation is related to a kind of nucleolus protein named Nopp140, and its appearance is an important marker of endometrial receptivity. This article is to review relationship between endometrial receptivity and Nopp140. |
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| Keywords: | Nopp140 |
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