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F-18 FDG PET/CT evaluation of radiotherapy response in rare case of mucosa-associated lymphoid tissue lymphoma
Authors:Ryogo Minamimoto  Ukihide Tateishi  Naoto Tomita  Yoshiaki Inayama  Motoko Omura-Minamisawa  Yoshibumi Tayama  Masaharu Hata  Yoshinobu Kubota  Tomio Inoue
Institution:(1) Department of Radiology, Graduate School of Medicine, Yokohama City University, 3-9 Fukuura, Kanazawa-ku, Yokohama Kanagawa, 236-0004, Japan;(2) Department of Hematology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan;(3) Division of Anatomic and Surgical Pathology, Hospital of Yokohama City University, Yokohama City University School of Medicine, Yokohama, Japan;(4) Department of Urology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan
Abstract:We experienced two cases of mucosa-associated lymphoid tissue (MALT) lymphoma arising at unusual locations and used F-18 fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) to evaluate their response to radiation therapy (RT). A 62-year-old male with proven prostatic MALT lymphoma and a 43-year-old woman with proven duodenal MALT lymphoma had diffuse FDG uptake in the lesion. Both cases were treated with RT; following FDG, PET/CT showed decreased FDG uptake in each lesion. Neither patient had evidence of recurrence at more than 18 months after RT. FDG PET/CT is useful for indicating the treatment site in MALT lymphoma and in evaluation of therapeutic response following RT.
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