| 三金片对女性再发性尿路感染患者外周血T淋巴细胞亚群的影响 |
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| 引用本文： | 殷敏,张慧,徐新春,陈以平. 三金片对女性再发性尿路感染患者外周血T淋巴细胞亚群的影响[J]. 中国中药杂志, 2011, 36(16): 2294-2296 |
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| 作者姓名： | 殷敏 张慧 徐新春 陈以平 |
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| 作者单位： | 1. 上海市徐汇区中心医院,上海,200031
2. 上海中医药大学附属龙华医院,上海,200032 |
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| 摘 要： | 目的:通过观察三金片对女性再发性尿感患者外周血T淋巴细胞亚群的影响,从而揭示该药防治尿感的免疫学药理机制.方法:采用随机、对照、开放的方法,68例患者分为治疗组30例,对照组28例,2组均予常规敏感抗生素治疗,治疗组加服三金片,在尿菌转阴后,治疗组予三金片维持治疗3个月；对照组予相应低剂量抗生素维持治疗3个月.观察2组治疗前后外周血T淋巴细胞水平、2组自起始治疗至尿菌培养转阴时所用治疗时间以及分别在停药3个月后2组尿感的再发率.结果:治疗组患者在外周血CD3+,CD4+T细胞以及CD4+/CD8+等方面均较治疗前提高(P＜0.05),并较对照组有统计学差异(P＜0.05),治疗组患者自起始治疗至尿菌培养转阴时所用治疗时间较对照组显著减短(P＜0.01)；2组在分别停药3月后,治疗组较对照组尿感再发率显著降低(P＜0.01).结论:三金片能通过改善女性再发性尿感患者细胞免疫水平,而达到缩短疗程、降低再发率等疗效.
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| 关 键 词： | 三金片 再发性尿路感染 T淋巴细胞亚群 临床研究 |
| 收稿时间： | 2011-06-07 |
Effects of Sanjin tablets on T lymphocyte subsets of peripheral blood of women with recurrent urinary tract infection |
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| YIN Min,ZHANG Hui,XU Xinchun and CHEN Yiping. Effects of Sanjin tablets on T lymphocyte subsets of peripheral blood of women with recurrent urinary tract infection[J]. China Journal of Chinese Materia Medica, 2011, 36(16): 2294-2296 |
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| Authors: | YIN Min ZHANG Hui XU Xinchun CHEN Yiping |
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| Affiliation: | Shanghai Xuhui Central Hospital, Shanghai 200031,China;Shanghai Xuhui Central Hospital, Shanghai 200031,China;Shanghai Xuhui Central Hospital, Shanghai 200031,China;Shanghai Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China |
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| Abstract: | Objective: To observe the impact of Sanjin tablet on the T lymphocyte subsets of the peripheral blood of female patients with recurrent urinary tract infection,to reveal the immune pharmacological mechanism of its prevention and treatment of the disease.Method: A randomized,controlled and open trial was adopted.The 68 patients were divided into treatment group(30 cases) and control group(28 cases).Two groups were both treated with conventional sensitive antibiotics,the treatment group took Sanjin tablet in ... |
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| Keywords: | Sanjin tablet recurrent urinary tract infection T lymphocyte subsets clinical research |
| 本文献已被 CNKI 万方数据 PubMed 等数据库收录！ |
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