| 三氧化矿物凝聚体(MTA)的研究进展 |
| |
| 引用本文： | 周欣,张成飞. 三氧化矿物凝聚体(MTA)的研究进展[J]. 牙体牙髓牙周病学杂志, 2004, 14(11): 647-650 |
| |
| 作者姓名： | 周欣 张成飞 |
| |
| 作者单位： | 北京大学口腔医学院,北京,100081 |
| |
| 摘 要： | 一种新型生物材料，三氰化矿物凝聚体(Mineral trioxide aggregate MTA)，广泛应用于牙科治疗中的直接盖髓、活髓切断、根尖成形、髓室底穿孔及根管侧穿修补、根管倒充填等多个领域。体外和体内试验证实，MTA具有良好的生物相容性，可有效促进硬组织的再生，并且具有一定的抗菌和抑菌性,对组织无毒其持久的封闭性大大提高了侧穿修补和根尖倒充填的成功功率、MTA可通过调节细胞因子的分泌，激活细胞外信号调节性激酶活性和促进骨钙素的表达等途径，影响骨的吸收和改建，进而促促进病变的愈合.虽然MTA也有其局限性，但仍是一种极具潜力的牙科新型材料。
|
| 关 键 词： | 三氧化矿物凝聚体 穿孔修补 根治治疗 |
| 文章编号： | 1005-2593(2004)11-0647-04 |
| 修稿时间： | 2004-07-20 |
Present research of mineral trioxide aggregate |
| |
| ZHOU Xin. Present research of mineral trioxide aggregate[J]. Chinese Journal of Conservative Dentistry, 2004, 14(11): 647-650 |
| |
| Authors: | ZHOU Xin |
| |
| Abstract: | A novel material, Mineral trioxide aggregate( MTA),has been widely used in dentistry for pulp-capping,pulpotomy,apexification ,root perforation repair and root-end filling.In vitro and in vivo exper iments demonstrate that MTAhaswell biocompatibility,which can promote the re generation of hard tissue.It is bactericidal and bacteriostatic,and not cytotoxi c to the tissue.The long sealing ability enhanced the success rate of root perfo ration repair and root-end filling.In addition, MTA can influence the absorptio n and regeneration of bone by regulating the secretion of cytokine,activating th e extracellular regulated kinases and promoting the expression of osteocalcin.Inconclusion,MTA is a potential material for dentistry. [ |
| |
| Keywords: | mineral trioxide aggregate perforation repair root canal treatment |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
