| 海文螺旋藻健血片对动物造血功能的影响 |
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| 引用本文： | 刘维俊,黄光才,叶小倩,许春琴,瞿金玲,尹江. 海文螺旋藻健血片对动物造血功能的影响[J]. 中国海洋药物, 1996, 15(1) |
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| 作者姓名： | 刘维俊 黄光才 叶小倩 许春琴 瞿金玲 尹江 |
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| 作者单位： | 海南省药品检验所药理室，海南省药品检验所药理室，海南省药品检验所药理室，海南省药品检验所药理室，海南海文药物研究中心，海南海文药物研究中心 海口 570102，海口 570102，海口 570102，海口 570102 |
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| 摘 要： | 海文螺旋藻健血片(HLJ)按3.0/kg和6.0g/kg给小白鼠灌胃,对腹腔注射环磷酰胺(CTX)引起的小鼠网织红细胞下降有保护作用(P<0.01),对骨髓有核细胞下降和脾脏重量下降无保护作用(P>0.05);对皮下注射苯诱法的小鼠网织红细胞下降,血红蛋白下降和脾脏重量下降均有一定的保护作用(P<0.01),但对骨髓有核细胞下降无保护作用;对大鼠人工心脏失血性贫血,6.0g/kg剂量组有促进血红蛋白升高的作用(P<0.01)。
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| 关 键 词： | 螺旋藻 网织红细胞 血红蛋白 失血性贫血 |
EFFECTS OF HAIWEN LUOXUANZAO JIANXUEPIAN (HLJ) ON HEMOPOIETIC FUNCTIONS IN MICE |
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| Liu Weijun,Huang Guangcai.Ye Xiaoqing.et al.. EFFECTS OF HAIWEN LUOXUANZAO JIANXUEPIAN (HLJ) ON HEMOPOIETIC FUNCTIONS IN MICE[J]. Chinese Journal of Marine Drugs, 1996, 15(1) |
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| Authors: | Liu Weijun Huang Guangcai.Ye Xiaoqing.et al. |
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| Abstract: | Administrated to mice i. g. in the dosages of 3. 0 g/kg and 6. 0 g/kg,Haiwen Luoxuanzao Jianxuepian (HLJ) improved the decrease of reticulocytes induced by Cyclophos-phamide (CTX) i. p. (P <0. 01). But it had no protective effects on the decrease of-ery-throblast in bone marrow and weight of the spleen ( P X). 05). It increased the number of reticulocytes, quantity of hemoglobin and weight of mice spleen which were injected with benzene s. b. ( P <0. 01). However.it did not interfere in the decrease of erythroblast in bone marrow induced by benzene. It also promoted the quantity of hemoglobin in the case of anemia caused by artifical depletion from the heart. |
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| Keywords: | S pirulina reticulocyte hemoglobin pqsthemorrhagic anemia |
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