体描仪测定哮喘儿童和成人肺功能的临床意义

目的探讨人体体积描记仪(人体体描仪)测定哮喘儿童和成人肺功能的临床意义.方法采用人体体描仪测定哮喘发作期儿童及成人治疗前后的肺功能,比较第1秒用力呼气容积(FEV1)、用力呼气肺活量(FVC)、第1秒用力呼气容积占用力呼气肺活量比值(FEV1/FVC)、最大呼气流量(PEF)和用力呼气25%、50%肺活量时瞬间流量(FEF25%、FEF50%)等肺功能指标的变化幅度.结果治疗前儿童和成人组PEF异常率分别为92.58%和86.36%,治疗后上述指标均有不同程度提高,差异显著(均为P<0.001);两组间肺功能变化幅度除PEF(P>0.05)外,FVC、FEV1、FEV1/FVC、FEF25%、FEF50%差异均有显著性(均为P<0.01).结论采用人体体描仪进行肺功能测定有利于哮喘诊断和发作期病情评估,更适合于年长儿童肺功能指标的监测.

Clinical significance of testing pulmonary function with auto-body plethysmograph in children and adults with asthma

Objective To evaluate the clinical significance of pulmonary function with auto-body plethysmograph in children and adults with asthma.Method The pulmonary function of pretherapy and of post-treatment was evaluated with auto-body plethysmograph in children and adults with asthma, and the changes of forced expiratory volume in 1 sec (FEV 1),forced vital capacity (FVC),FEV 1/FVC,peak expiratory flow(PEF),forced mid-expiratory flow rate (FEF 25%,FEF 50%) were measured. Results 25 of 27 cases in children(92.58%) and 19 case of 22 adults (86.36%) were abnormal in PEF before treatment. The values of FEV 1,FVC,FEV 1/FVC,FEF 25%,FEF 50% in post-treatment in both groups were increased significantly(P<0.01). Conclusion Determination on pulmonary function by auto-body plethysmograph is valuable on the diagnosis and treatment of asthma.