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Impact of mGluR5 during amphetamine-induced hyperactivity and conditioned hyperactivity in differentially reared rats |
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| Authors: | Margaret?J.?Gill author-information" > author-information__contact u-icon-before" > mailto:gillm@musc.edu" title=" gillm@musc.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author,Jennifer?C.?Arnold,Mary?E.?Cain |
| Affiliation: | (1) Department of Psychology, Kansas State University, 492 Bluemont Hall, Manhattan, KS 66506, USA;(2) Department of Neuroscience, Medical University of South Carolina, 173 Ashley Ave, BSB 416 E, Charleston, SC 29425, USA |
| Abstract: | Rationale3-((2-Methyl-1,3-thiazol-4-yl)ethynyl)pyridine hydrochloride (MTEP) is a metabotropic glutamate receptor 5 (mGluR5) antagonist that may alter drug sensitivity in differentially reared rats due to its involvement in the psychostimulant reward pathway and plasticity. |
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