(2-Methoxyethoxy)acetic acid: a urinary biomarker of exposure for jet fuel JP-8期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

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(2-Methoxyethoxy)acetic acid: a urinary biomarker of exposure for jet fuel JP-8

Authors:	Email author" target="_blank">Clayton?B’Hymer Email author Patricia?Mathias Jr" target="_blank">Edward?KriegJr Kenneth?L?Cheever Christine?A?Toennis John?C?Clark James?S?Kesner Roger?L?Gibson Mary?Ann?Butler

Institution:	(1) U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, Division of Applied Research and Technology, Taft Laboratory, 4676 Columbia Parkway, Cincinnati, OH 45226, USA;(2) Preventive Medicine and Biometric Department, Uniform Services University, Room A1040H, 4301 Jones Bridge Road, Bethesda, MD 20814, USA

Abstract:	Purpose To demonstrate the utility of the urinary metabolite (2-methoxyethoxy)acetic acid (MEAA) as a biomarker of exposure. 2-(2-methoxyethoxy)ethanol diethylene glycol monomethyl ether] is an anti-icing agent used in the formulation of JP-8, and it is added at a known uniform 0.1% (v/v) concentration to each batch lot. JP-8 is a kerosene-based fuel containing different compounds that vary in the content of every batch/lot of fuel; thus, MEAA has the potential to be a more specific and a consistent quantitative biomarker for JP-8 exposure.

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