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经颞浅动脉灌注氟尿嘧啶和卡铂治疗舌癌
引用本文:曾东林,王国华,廖煜. 经颞浅动脉灌注氟尿嘧啶和卡铂治疗舌癌[J]. 口腔医学, 2005, 25(6): 351-352
作者姓名:曾东林  王国华  廖煜
作者单位:中山大学第二附属医院口腔颌面外科,广州,510120;桂林医学院附属医院口腔科,桂林,541001
摘    要:目的探讨术前联合应用氟尿嘧啶、卡铂诱导化疗治疗舌癌的临床效果。方法20例舌癌患者经颞浅动脉插管连续顺序灌注氟尿嘧啶和卡铂,比较化疗前、后原发肿瘤灶的大小,并记录化疗的主要不良反应。结果完全缓解(CR)18例(90%),部分缓解(PR)2例(10%),总有效率(CR+PR)100%;不良反应轻微。结论经颞浅动脉插管灌注氟尿嘧啶和卡铂是治疗舌癌的一种有效方法,不良反应发生率低且轻。

关 键 词:氟尿嘧啶  卡铂  颞浅动脉灌注  口腔肿瘤  化疗
文章编号:1003-9872(2005)06-0351-02
收稿时间:2005-05-20
修稿时间:2005-05-20

Arterial infusion fluorouracil and carboplatin through superficial temporal artery for tongue carcinoma
ZENG Dong-lin,WANG Guo-hua,LIAO Yu. Arterial infusion fluorouracil and carboplatin through superficial temporal artery for tongue carcinoma[J]. Stomatology, 2005, 25(6): 351-352
Authors:ZENG Dong-lin  WANG Guo-hua  LIAO Yu
Affiliation:Department of Oral and Maxillofacial Surgery, the Second Affiliated Hospital of Zhongshan University, Guangzhou, 510120, China
Abstract:Objective To investigate the clinical effects of the adjuvant chemical therapy of tongue carcinoma using fluorouracil and carboplatin.Methods Twenty cases with tongue carcinoma were treated by arterial infusion fluorouracil and carboplatin through the superficial temporal artery before surgical operation.The size of the tumor before and after treatment and the main complication of each case after treatment were studied.Results Eighteen of the twenty(90%) patients had a complete response to arterial infusion chemotherapy and two(10%) had a partial response.The complication of chemotherapy was slight.Conclusion Arterial infusion fluorouracil and carboplatin through the superficial temporal artery is an effective method for the therapy of tongue carcinoma.
Keywords:fluorouracil   carbeplatin   arterial infusion through superficial temporal artery   oral tumor   chemotherapy
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