| 含锶磷酸钙骨水泥生物相容性评价 |
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| 引用本文： | 李峰,赵信义,吴军正,李焰. 含锶磷酸钙骨水泥生物相容性评价[J]. 牙体牙髓牙周病学杂志, 2006, 16(5): 264-268 |
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| 作者姓名： | 李峰 赵信义 吴军正 李焰 |
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| 作者单位： | 第四军医大学口腔医学院材料学教研室,陕西,西安,710032 |
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| 摘 要： | 目的：评价新型含锶磷酸钙骨水泥的生物相容性和安全性，从而为其在骨缺损修复领域中的临床运用提供依据。方法：分别进行急性毒性试验、热原试验、溶血试验、短期肌肉植入试验、骨内植入试验等生物相容性试验。结果：这种含锶磷酸钙骨水泥材料无毒，无热原性，植入兔肌肉和骨内后逐渐发生降解。结论：含锶磷酸钙骨水泥材料具有良好的生物相容性。
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| 关 键 词： | 锶 磷酸钙骨水泥 生物相容性 |
| 文章编号： | 1005-2593（2006）05-0264-05 |
| 收稿时间： | 2005-12-13 |
| 修稿时间： | 2006-03-06 |
Biocompatibility of strontium containing calcium phosphate cement |
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| LI Feng,ZHAO Xin-yi,WU Jun-zheng,LI Yan. Biocompatibility of strontium containing calcium phosphate cement[J]. Chinese Journal of Conservative Dentistry, 2006, 16(5): 264-268 |
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| Authors: | LI Feng ZHAO Xin-yi WU Jun-zheng LI Yan |
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| Abstract: | AIM: To study the biocompatibility and safety of strontium containing calcium phosphate cement for the clinical use in the bone reconstruction. METHODS: The biocompatibility was evaluated through the experiments including acute systemic toxicity test,pyrogen test,and short-term muscle and bone implant test. RESULTS: All results indicated that the material had no toxicity,no irritation, and did not contain the pyrogen material. In muscle and bone implant test the material was degradated gradually. CONCLUSION: The strontium containing calcium phosphate cement possesses excellent biocompatibility. |
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| Keywords: | strontium calcium phosphate cement biocompatibility |
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