| γ-干扰素和白介素抗弓形虫感染研究进展 |
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| 引用本文： | 聂大平,李伟,申丽洁,尤英霞. γ-干扰素和白介素抗弓形虫感染研究进展[J]. 中国病原生物学杂志, 2012, 0(7): 547-549 |
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| 作者姓名： | 聂大平 李伟 申丽洁 尤英霞 |
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| 作者单位： | 大理学院基础医学院寄生虫学教研室;昆明医学院寄生虫学教研室 |
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| 基金项目： | 国家自然科学基金项目(No.30960330) |
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| 摘 要： | 刚地弓形虫(Toxoplasma gondii)是一种专性有核细胞内寄生虫,可以感染包括人类在内的几乎所有温血动物,能引起严重的人兽共患弓形虫病。宿主体内γ-干扰素和白介素的水平影响弓形虫的垂直传播并决定弓形虫病的发生与转归,γ-干扰素和白介素在宿主抗弓形虫感染中有着重要的作用。本文对γ-干扰素和白介素抗弓形虫感染研究进展进行了综述。
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| 关 键 词： | 弓形虫 γ-干扰素 白介素 综述 |
Advances in the study of interferon-gamma and interleukin in Toxoplasma gondii infection |
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| NIE Da-ping,LI Wei,SHEN Li-jie,YOU Ying-xia. Advances in the study of interferon-gamma and interleukin in Toxoplasma gondii infection[J]. Journal of Pathogen Biology, 2012, 0(7): 547-549 |
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| Authors: | NIE Da-ping LI Wei SHEN Li-jie YOU Ying-xia |
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| Affiliation: | 1(1.Department of Parasitology,College of Basic Medical,Dali University,Dali,Yunnan 671003,China;2.Department of Parasitology,Medical College of Kunming,Kunming 650500,China) |
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| Abstract: | Toxoplasma gondii is a protozoan parasite of nucleated cells that can infect nearly all warm-blooded animals,including humans,and cause serious zoonosis in the form of toxoplasmosis.Gamma-interferon and interleukin levels in the host’s body affect the vertical transmission of T.gondii and determine the development and prognosis of toxoplasmosis.These cytokines play an important role in the host’s resistance to T.gondii infection.This article reviews advances in gamma-interferon and interleukins to fight T.gondii infection |
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| Keywords: | Toxoplasma Gondii gamma-interferon interleukin review |
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