快速眼动睡眠行为障碍严重程度量表在特发性快速眼动睡眠行为障碍中的应用

目的探讨应用快速眼动睡眠行为障碍(RBD)严重程度量表(RBDSS)评价特发性RBD(iRBD)患者症状特点的异质性。方法选取iRBD患者118例,根据RBDSS评分分为亚临床RBD组(亚临床组)26例和症状性RBD组(症状组)92例。行视频-多导睡眠仪监测以及RBDSS评分并进行分析。结果症状组中伴有典型近端肢体活动及声音表现47例,占39.8%,远端肢体活动及声音表现为28例,占23.7%,轴向运动及声音表现为17例,占14.4%;亚临床组26例,占22.0%,差异有统计学意义(P<0.01)。2组各项睡眠参数比较,差异无统计学意义(P>0.05)。结论应用RBDSS可以评估iRBD患者的症状特点,并根据iRBD患者症状特点,采取不同的临床保护措施以及制定个体化治疗方案。

Application of rapid eye movement sleep behavior disorder severity scale in patients with iRBD

Objective To study the application of rapid eye movement(REM)sleep behavior disorder severity scale in assessment of the clinical features of patients with idiopathic REM sleep behavior disorder.Methods One hundred and eighteen patients with idiopathic REM sleep behavior disorder who underwent video pdysomnography were scored according to the REM sleep behavior disorder severity scale.Results Of the 118 patients with idiopathic REM sleep behavior disorder,47(39.8%)showed typical proximal extremity movements and vocalization,26(22.0%)displayed subclinical REM sleep behavior disorder,28(23.7%)demonstrated distal extremity movements and vocalization,and 17(14.4%)revealed axial movements and vocalization(P<0.01).No significant difference was found in sleep parameters between those with typical or subclinical REM sleep behavior disorder(P>0.05).Conclusion REM sleep behavior disorder severity scale can be used in assessment of the clinical features of patients with idiopathic REM sleep behavior disorder.Different clinical protective measures should be taken and different treatment protocals should be made for patients with idiopathic REM sleep behavior disorder according to their clinical features.