H型高血压患者动态血压的特点

目的:分析H型高血压患者动态血压的表现及特点。方法:连续入选自2010年1月至2013年3月,于我院住院的高血压患者,根据血清同型半胱氨酸(Hcy)水平将患者分为非H型高血压组(Hcy10μmol/L,A组)和H型高血压组(Hcy≥10μmol/L,B组),其中B组患者又分为B1组(Hcy20μmol/L)和B2组(Hcy≥20μmol/L)。所有患者均接受动态血压监测,对比分析两种类型高血压患者动态血压的特点。结果:本研究共入选高血压患者242例,其中H型高血压组(B组)患者136例(56.2%)。与非H型高血压患者相比,H型高血压患者动态血压,表现为非勺型和反勺型者均明显增多(非勺型:75.7%vs.34.9%,P0.001;反勺型:33.1%vs.18.9%,P=0.017),晨峰血压水平明显升高(169±10)vs.(160±7)mmHg(1mmHg=0.133kPa),P=0.036]。进一步亚组分析显示,B2组患者反勺型血压明显高于B1组(43.8%vs.23.6%,P=0.013),晨峰血压水平也明显高于B1组(174±9)vs.(166±9)mmHg,P=0.042]。结论:与非H型高血压患者相比,H型高血压患者的动态血压表现为非勺型及反勺型者明显增多,晨峰血压明显增高。

Ambulatory blood pressure characteristics of patients with hypertension

Objective：To investigate the ambulatory blood pressure characteristics of patients with H hypertension.Methods：We consecutively enrolled patients with hypertension admitted in our hospital from January 2010 to March 2013.According to the serum level of homocysteine （Hcy）,all the patients were divided into non-H hypertension group （Hcy ＜ 10μ mol/L,A group） and H hypertension group （Hcy ≥ 10μmol/L,B group）.The patients of B group were further divided into B2 group （Hcy ≥20μmol/L） and B1 group （Hcy ＜20μmol/L）.Ambulatory blood pressure monitoring y performed for all the patients.Results：Totally 242 patients were enrolled into our study,136 patients were diagnosed as H hypertension （56.2％）.Compared with those with non-H hypertension,patients with H hypertension have higher rate of non-dipping （75.7 vs.34.9） ％,P ＜ 0.001] and anti-dipping blood pressure pattern （33.1 vs.18.9）％,P =0.017] and higher level of morning blood pressure surge（169 ± 10） vs.（160 ±7） mmHg（1mmHg =0.133kPa）,P =0.036].Compared with B1 group,B2group patients have higher rate of anti-dipping blood pressure pattern （43.8 vs.23.6） ％,P =0.013] and higher level of morning blood pressure surge （174 ± 9） vs.（166 ± 9） mmHg,P =0.042].Conclusion：Patients with H hypertension have higher rate non-dipping blood pressure pattern and higher level of morning blood pressure surge.