高钠血症对神经重症患者的影响

目的探讨高钠血症在神经重症患者中的发生率,及其对住院患者病死率、住院时间和住院费用的影响。方法回顾性分析2011年1¹2月本院收治的神经ICU重症患者274例,死亡52例,存活222例。将血清钠>150mmol/L定义为高钠血症,并进行统计学分析。结果死亡患者中高钠血症26例,存活患者23例,两者比较差异有统计学意义(50.0%vs 10.4%,P=0.000)。高钠血症是神经重症患者死亡的独立风险因素(OR=5.08,95%CI:2.2112月本院收治的神经ICU重症患者274例,死亡52例,存活222例。将血清钠>150mmol/L定义为高钠血症,并进行统计学分析。结果死亡患者中高钠血症26例,存活患者23例,两者比较差异有统计学意义(50.0%vs 10.4%,P=0.000)。高钠血症是神经重症患者死亡的独立风险因素(OR=5.08,95%CI:2.21¹1.63,P=0.000)。高钠血症患者与住院费用呈正相关,但差异无统计学意义(β=0.023,P=0.756);高钠血症患者与住院天数呈正相关,差异无统计学意义(β=0.094,P=0.200)。结论高钠血症在神经重症患者中具有更高的发生率,而且是神经重症患者死亡的独立风险因素,且与患者住院时间与住院费用呈正相关。

Effect of hypernatremia mortality,hospital stay time and cost in neurocritically ill patients

Objective To study the incidence of hypernatremia and its effect on mortality,hospital stay time and cost in neurocrtically ill patients.Methods The clinical data about 274 neurocritically ill patients(52died,222survived)admitted to our department were retrospectively analyzed.Hypernatremia was diagnosed when the serum sodium level was>150mmol/L.ResultsOf the 52 died patients and the 222 survived patients,26(50.0%)and 23(10.4%)were diagnosed with hypernatremia respectively(P=0.000).Hypernatremia was an independent risk factor for the death of neurocritically ill patients(OR=5.08,95%CI:2.21-11.63,P=0.000)and was positively related with their hospital stay time(days)and cost although no significant difference was found between them(β=0.023,P=0.756;β=0.094,P=0.200).Conclusion The incidence of hypernatremia is high in neurocritically ill patients.Hypernatremia is an independent risk factor for their death and positively related with their hospital stay time and cost.