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EFFECTS OF ARTEMETHER ON PERIPHERAL T,B,Tμ AND Tγ LYMPHOCYTES IN BEAGLE DOG
引用本文:顾远锡,崔玉芳,邬伯安,石笑春,滕翕和.EFFECTS OF ARTEMETHER ON PERIPHERAL T,B,Tμ AND Tγ LYMPHOCYTES IN BEAGLE DOG[J].中医杂志(英文版),1989(3).
作者姓名:顾远锡  崔玉芳  邬伯安  石笑春  滕翕和
作者单位:Institute of Radiation Medicine Academy of Military Medical Sciences,Institute of Radiation Medicine,Academy of Military Medical Sciences,Institute of Microbiology and Epidemiology,Institute of Microbiology and Epidemiology,Institute of Microbiology and Epidemiology
摘    要:The effects of intramuscular injection of Arte-mether on peripheral T,B,Tμ and Tγ lymphocytesin beagle dogs was investigated cytochemically.Dosesused were 6,19,and 32 MKD,respectively.Resultsshowed that after injection of Artemether for 15successive days,the T,B,and Tμ lymphocyes of the19 and 32 MKD groups were markedly reduced andthe Tγ lymphocytes of all 5 dosage groups weredecreased to zero.28 days after cessation of thedrug.T,Tμ and Tγ lymphoctes had recovered tocontrol levels,while the B lymphocytes of the 19 and32 MKD groups remained markedly lower thanthose of the control groups.The differences and similarities of the effectson the peripheral T,B,Tμ and Tγ,lymphocytes pro-duced by the 3 dosages of Artemether and the re-lationship between the changes of T,B lymphocytesand immunological function of beagle dogs arc dis-cussed.

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