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Pregnancy and birth after intracytoplasmic sperm injection with totally immotile sperm recovered from the ejaculate |
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| Authors: | Alberto Barros M.D.,Ph.D.,Má rio Sousa M.D.,Ph.D.,Cristiano Oliveira M.D.,Joaquina Silva M.D.,Vasco Almeida Ph.D.,Jorge Beires M.D. |
| Affiliation: | a Laboratory of Medical Genetics, Faculty of Medicine, University of Porto, Porto, Portugal b Laboratory of Cell Biology, Institute of Biomedical Sciences, University of Porto, Porto, Portugal c Department of Obstetrics and Gynecology, Padre Américo Hospital of Vale do Sousa, University of Porto, Porto, Portugal d Institute of Anthropology, Faculty of Sciences, Porto, Portugal e Department of Obstetrics and Gynecology, St. John Academic Hospital of Porto, Porto, Portugal |
| Abstract: | Objective: To report the birth of two healthy children after intracytoplasmic sperm injection (ICSI) with totally immotile spermatozoa recovered from the ejaculate. Design: Retrospective case report. Setting: University-based hospital. Patient(s): Four couples in whom spermatozoa recovered from the ejaculate were totally immotile but presented normal vitality scores. Intervention(s): Therapeutical IVF-ET attempts coupled with ICSI. Main Outcome Measure(s): Fertilization and pregnancy results after ICSI. Results: With random sperm injection, 19 of the 36 injected oocytes showed normal fertilization and cleavage. One of four patients had a twin pregnancy that resulted in birth of two healthy children. Conclusion(s): In cases in which totally immotile ejaculated sperm present normal vitality scores, normal clinical outcomes can be achieved by using the usual random sperm selection during conventional ICSI. |
| Keywords: | Ejaculated totally immotile sperm intracytoplasmic sperm injection pregnancy |
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