| 血清TRAb测定在Graves病诊治中的临床意义的探讨 |
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| 引用本文： | 薛声能,雷娟,刘顺莲.血清TRAb测定在Graves病诊治中的临床意义的探讨[J].国际医药卫生导报,2005,11(24):22-23. |
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| 作者姓名： | 薛声能 雷娟 刘顺莲 |
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| 作者单位： | 中山大学附属第二医院,广东,广州,510120;中山大学附属第二医院,广东,广州,510120;中山大学附属第二医院,广东,广州,510120 |
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| 摘 要： | 目的探讨血清促甲状腺激素受体抗体（TRAb）水平的改变在Graves病（GD）的诊断、治疗和复发中的临床意义。方法把385例GD患者分为初诊组、缓解组和复发组，对照组为85例健康人。对所有对象进行TRAb水平的测定，所得结果进行统计学分析处理。结果GD各组的TRAb阳性率明显高于对照组（P〈0．05）初诊组和复发组的TRAb阳性率明显高于缓解组（P〈0．05）。结论GD患者血中TRAb浓度升高，对其水平的检测在诊断、治疗及随访复发中具有重要价值。
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| 关 键 词： | Graves病 促甲状腺激素受体抗体 |
| 文章编号： | 1007-1245（2005）24-0022-02 |
| 收稿时间： | 2005-06-27 |
| 修稿时间： | 2005年6月27日 |
Clinical Significance of Determining Serum TRAb in the Diagnosis and Treatment of Graves Disease |
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| Xue Shengneng,Lei Juan,Liu Shunlian.Clinical Significance of Determining Serum TRAb in the Diagnosis and Treatment of Graves Disease[J].International Medicine & Health Guidance News,2005,11(24):22-23. |
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| Authors: | Xue Shengneng Lei Juan Liu Shunlian |
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| Abstract: | Objective To explore the significance of determination of TSH receptor antibody (TRAb) in the diagnosis, treatment and relapse of Graves disease (GD). Methods 385 cases of suffering from GD were divided into 3 groups: untreated group, modified group and relapsing group. The control group was 85 cases of healthy volunteers. The levels of TRAb in blood were estimated in each group. Statistical evaluation was carried out in all of the results. Results The positive rate of each group with GD was significantly higher than that of control group. Positive rates of untreated group and relapsing group were significantly higher than that of modified group.Conclusion The level of TRAb in blood increased in Graves disease. Determination of serum TRAb level was helpful for the diagnosis, treatment and relapse in Graves disease. |
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| Keywords: | Graves disease thyrotrophic receptor antibody (TRAb) |
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