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Evaluation of genes identified by microarray analysis in favorable neuroblastoma |
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| Authors: | Naomi Kamei Keiko Hiyama Hiroaki Yamaoka Arata Kamimatsuse Yoshiyuki Onitake Taijiro Sueda Eiso Hiyama |
| Affiliation: | (1) Department of Pediatric Surgery, Graduate School of Biomedical Science, Natural Center for Basic Research and Development, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan;(2) Department of Translational Cancer Research, Research Institute for Radiation Biology and Medicine, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan;(3) Department of Pediatric Surgery, Graduate School of Biomedical Science, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima 734-8551, Japan |
| Abstract: | PurposeThe biological heterogeneity of neuroblastoma results in a varied outcome ranging from spontaneous regression to fatal tumor progression. Microarray expression profiling and genetic polymorphism arrays may help identify key genes that differ in aggressive neuroblastomas from those observed in tumors associated with a favorable outcome. |
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