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DNA fingerprinting in leukemia
Authors:Seppo Pakkala
Affiliation:(1) Transplantation Laboratory, University of Helsinki, Haartmaninkatu 3, SF-00290 Helsinki, Finland
Abstract:Summary The detection of polymorphic regions of the human DNA provides individual specific markers, DNA fingerprints (DNA-F), for the identification of individuals. DNA-F can also be used for the detection of cell clones and serve as molecular markers of malignant disease. In leukemia DNA-F analysis can be used for the follow-up studies during remission or after bone marrow transplantation. Recent studies on DNA fingerprinting in leukemia are reviewed.
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