15例结节性硬化的临床及影像诊断

目的：探讨结节性硬化症（TS）的CT和MRI特征及临床表现。方法：回顾分析15例经临床和病理诊断的TS患者CT和MRI特征及临床表现，15例均行颅脑CT平扫，CT增强2例；4例行颅脑MRI平扫，MRI增强1例。结果：15例患者多以癫痫、智力低下就诊。CT表现为双侧侧脑室室管膜下多发高密度钙化结节13例，单发结节2例，1例并有室管膜下巨细胞星形细胞瘤。4例MRI均见双侧侧脑室室管膜下多发结节，T1WI呈低信号或等信号，T2WI则为低信号。结论：CT和MR对TS的诊断具有重要价值，患者的临床特点和影像学特征性表现相结合可对TS作出正确诊断。

Clinical and Imaging Diagnosis of Tuberous Sclerosis

Objective: To explore CT and MRI characteristic features of tuberous sclerosis(TS) and its clinical manifestations.Methods:CT and MRI features in patients with TS and their clinical manifestations were retrospectively reviewed;all patients were diagnosed through clinic and pathology.Each case underwent CT plain scanning of head while two cases underwent enhanced head CT.MRI of head was performed in 4 cases while only one case underwent enhanced head MRI.Results: All patients saw doctors mostly for their epilepsy and mental retardation.On CT scan,13 cases had multiple subependymal high-density calcified nodules,2 cases showed single nodule,Association with subependymal giant cell astrocytoma was found 1 case.4 cases had MRI,multiple subependymal nodules which were hypo intense or isointense on T1WI and hypo intense on T2WI could be revealed.Conclusions: CT and MRI play an important role in the diagnosis of TS;it can determine the nature of the patients with TS to combine their clinical characteristics with CT and MRI features.