脑前连合和后连合立体定向MRI研究及其临床意义

目的 研究健康中国人腩立体定向标志前连合(AC)、后连合(PC),为立体定向功能神经外科捉供基础数据.方法 采集健康中国成人自愿者脑MRJ图像120例,男女各60例.在正中矢状面上分别测量AC、PC的宽度和AC-PC的长度(LI),采用统计学方法 分析LI与年龄的相关性及性别差异,并将颅长纳入比较.结果 LI的长度在19.70～25.65 mm之间,平均为(22.92±1.13)mm;AC、PC平均宽度分别为(2.30±0.37)mm、(1.60±0.31)mm;本组中国成人各年龄段组人脑LI长度与年龄无相关性,男性LI长度大于女性,差异有统计学意义(P＜0.05),将颅长纳入比较后,这种差异性消欠了:AC、PC的宽度与年龄无相关性,AC的宽度女性大于男性,PC的宽度性别差异无统计学意义.结论立体定向功能神经外科中AC-PC线是稳定的脑内结构测量参考线.

Research on stereotactic MRI of AC and PC and its clinical significance

Objective To provide fundamental information and data for stereotacfic and functional neurosurgery through studying the characteristic anterior commissure (AC) and posterior commissure (PC) of stereotaxy for healthy Chinese brains. Methods Brain MR images of 120 healthy Chinese adult volunteers were acquired; half of them were males. The respective width of AC and PC and the length of AC-PC (LI) were measured in the medial sagittal plane; the gender difference of LI and its correlation with age were analyzed; the cranial length was also included for comparison. LI was analyzed between males and females and t-test was applied to assess the widths of AC and PC. Results LI was between 19.70 and 25.65 mm, with the mean value of (22.92±1.13) mm; the width of AC and PC was respectively (2.30±0.37) mm and (1.60±0.31) mm. There was no correlation between LI and age among age groups of Chinese adults; LI of males were longer than that of females, but the difference vanished after the cranial length was included for comparison. There was no correlation between the widths of AC and PC and age; the AC width of females was longer than that of males, but there was no gender difference in the width of PC. Conclusion AC-PC line is a stable reference line for the measurement of intracranial structures in stereotactic and functional neurosurgery.