244例药物不良反应分析报告

目的分析我院药品不良反应(ADR)发生特点和相关因素,制定新年度ADR监测工作方向。方法对我院2006年度所发生的244例ADR报告作回顾性分析。结果报告中40～69岁年龄段发生率最高;ADR涉及的药品种类及例次中,以抗生素、中药针剂领先;ADR临床表现上,主要是皮肤及其附件损害,其次是消化系统损害。结论加强药物药品不良反应监测,促进临床合理用药。

Analysis of 244 Cases of Adverse Drug Reactions in 2006

OBJECTIVE To analyse the characteristics and the related factors of adverse drug reactions(ADR) occurred in our hospital,and establish the way of ADR clinical monitor in the next year.METHODS Reviewed and analysed the reports of 244 cases of ADR occurred in our hospital in 2006.RESULTS Among the 244 cases of ADR,the patients at the age of 40 to 69 had the highest incidence;The primary reasons were found to be related to use of antibiotic drugs and traditional Chinese medical injections;ADR were mainly manifested as skin and local lesion,secondary as alimentary system lesion.CONCLUSION We should strengthen ADR clinical monitor and promote rational use of drugs in clinic.