| 复方磺胺甲噁唑片的胶束薄层色谱分析 |
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| 引用本文： | 米慕真,周密,宋红斌. 复方磺胺甲噁唑片的胶束薄层色谱分析[J]. 沈阳药科大学学报, 2000, 17(2) |
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| 作者姓名： | 米慕真 周密 宋红斌 |
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| 作者单位： | 沈阳药科大学基础部,沈阳,110015 |
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| 摘 要： | 以十二烷基硫酸钠 (SDS)水溶液为展开剂、聚酰胺薄膜为固定相 ,对复方磺胺甲唑片(复方新诺明 )中两组分进行定量分析 .磺胺甲基异唑 (SMZ)和甲氧苄氨嘧啶 (TMP)分别在4 0～ 12 0mmo/L和 3 5～ 10 5mmol/L范围内吸收峰面积和浓度呈良好的线性关系 .相关系数分别为 0 9995和 0 9998,回收率分别为 10 1 4%和 99 5 % ,RSD(% )分别为 0 5 8和 1 6 0 .
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| 关 键 词： | 正相胶束薄层色谱 复方磺胺甲噁唑片 甲氧苄氨嘧啶 磺胺甲噁唑 |
Determination of the Compound Sulfamethoxazole Tablets Using Micellar Thin Layer Chromatography |
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| Mi Muzhen,Zhou Mi,Song Hongbin. Determination of the Compound Sulfamethoxazole Tablets Using Micellar Thin Layer Chromatography[J]. Journal of Shenyang Pharmaceutical University, 2000, 17(2) |
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| Authors: | Mi Muzhen Zhou Mi Song Hongbin |
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| Abstract: | Two compositions of the Compound Sulfamethoxazole Tablets can be separated and quantified on polyamide TLC sheets,using aqueous micellar solution of sodium dodecylsulfate as the mobile phase.The linear relationships between the quantity of SMZ or TMP and their peek area are good.The correlation coefficients are 0.999 5 and 0.999 8 respectively.The average recoveries are 101.4% and 99.5%.RSD are 0.58% and 1.60%(n=3).It is a practical method for determining the Compound Sulfamethoxazole Tablets. |
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| Keywords: | micellar thin layer chromatography the Compound Sulfamethoxazole Tablets SMZ TMP |
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