甲状腺功能低下的骨皮质X线分析

目的 为甲状腺功能低下青少年骨皮质改变提供临床诊断依据。方法 对5-24岁甲状腺功能低下青少年69例骨皮质厚度进行测量,并与正常健康青少年300例按5岁一个年龄段比较分析。结果 甲状腺功能低下组与正常组比较,除5-9岁年龄段之女性无显著性差异外,其余均有显著性差异(P<0.05-0.01)甲状腺功能减低组69例中55例骨龄均在14岁以下。用其骨龄比较其男女组之间骨皮质改变无显著性差异。用甲状腺功能低下组骨龄分组与正常年龄组(骨龄与年龄一致)对比分析,两者骨皮质厚度无显著性差别(P<0.05)。结论 甲状腺功能低下者10岁后骨皮质改变是随着骨龄变化而变化。在同骨龄情况下与正常组相比较无明显骨皮质改变。正常组显示随着年龄的增加骨皮质渐增厚。

Measurement of youngsters' bone cortical thickness in normal and hypothyroidism

Objective To supply data for clinical diagnose for the bone cortical thickness changes in the hypothyroid youngsters. Methods This paper deals with the measmpent of 5-24 years of age normal and hypothy-roid bone cortical thickness, c ompares and analyses with a phase in 5 ages. Results CCT of all the hypothvroidism groups are lagged behind compared with the normal group of same age. (P < 0.05-0.01), except that 5-9 age phase of female group has no obvious change. 55 of 69 cases for hypothyroidism' s bone ages are wholly before 14 years old; there is no obvious difference affer the comparison between the bone ages of males and females in each group. Comparison between the hypothyroidism' s bone age in each group and the corresponding age group in the nomal group in CCT is no obvious difference. (P > 0.05) Conclusion CCT of hypothyroidism generally is in accordance with its bone age and that the change of hypothyroidism' s own CCT is not obviously lagged behind their own bone age.