外周动静脉同步换血治疗新生儿重度高胆红素血症

目的 观察外周动静脉双管同步换血疗法治疗新生儿高胆红素血症的安全性、疗效及内环境的变化.方法 对32例新牛儿高胆红素血症患儿采用外周动静脉双管同步换血,术中监测生命体征,换血前后行血常规、血生化、肝功能、血糖等检查,并进行分析比较.结果 换血前后总胆红素、间接胆缸素的平均换出率分别为52.5%、51.7%,换血后血红蛋...

The treatment being cured neonatal hyperbilirubinemia by exchange transfusion of peripheral arteriovenous

Objective To observe the safety, curative effect and variation of internal environment of treatment for neonatal hyperbilirubinemia by exchange transfusion of peripheral arteriovenous. Methods Exchange transfusion was performed through the peripheral vessels on 15 cases of hyperbilirubinemia. The blood routine, blood biochemical test, hepatic function and serum glucose were measured before and after exchange transfusion. And the results were analyzed and compared. Results The rate of exchange to bilirubin (TSB), indirect bilirubin (IBIL) before and after exchange transfusion were 52.5% and 51.7% respectively. The hemoglobin after exchange transfusion was much higher than that before exchange transfusion (P＜0.05), white blood cell, platelet and potassium were significantly lower (P＜0.01), serum glucose might be increased sometime, but without statistic significant difference. The Na+ and Ca2+ had no obvious change before and after exchange transfusion. Conclusion Exchange transfusion of peripheral arteriovenous for neonatal hyperbilirubinemia treatment is safely effective with simple operation, although there were internal environment changes such as blood biochemical test abnormal, plate-reduction, but they could recover through self-adjustment and there was no obvious complication. The treatment was safe with the vital signs and blood related projects monitoring.