无明确诊断意义的宫颈非典型鳞状细胞的临床意义

目的探讨无明确诊断意义的宫颈非典型鳞状细胞对宫颈病变及处理的临床意义。方法对2009年1月至2010年12月间在我院进行宫颈细胞涂片检查的患者资料进行回顾性分析。结果共有86例患者为无明确诊断意义非典型鳞状细胞（ASCUS），结合阴道镜检查、病理检查、人乳头瘤病毒（HPV）检测，诊断为慢性宫颈炎的45例（52.3％），诊断为明确官颈上皮内瘤变（CIN）的有41例（47．7％）。HPV检测呈阳性的有49例（57．0％），在HPV阳性患者中，宫颈上皮内瘤变CINⅡ级及以上的有16例，占阳性患者的32．3％。宫颈癌2例，占4．1％，而阴性患者中无CINⅡ级及以上和癌变病例。结论结合阴道镜、病理检查以及HPV检测有利于对ASC患者的分流管理，对患者具重要的临床意义。

The clinical significance of atypical squamous cells of undetermined significance

Objective To explore the clinical significance of atypical squamous cells of undetermined significance ( ASCUS ) in cervical lesions. Methods The data on the patients who had received Pap smear in our hospital from January 2009 to December 2010 were retrospectively analyzed. Results Of All the patients, 86 were diagnosed as ASCUS. With the findings of vaginoscopy, pathological examination, and HPV detection, 45 patients ( 52.3% ) were diagnosed as chronic cervicitis, 41 (47.7% ) as cervical intraepithelial neoplasia ( CIN ), and 49 ( 57.0% ) as HPV positive. Of the 49 HPV positive patients, 16 were diagnosed as CIN Ⅱ and above, 2( 4.1% )as cervical cancer. There were no CIN Ⅱ and above or malignant tumors in HPV negative patients. Conclusions It is beneficial for managing the patients based on the clinical diagnosis combined with the findings of vaginoscopy, pathological examination, and HPV detection.