阿扎司琼联合小剂量地塞米松预防无痛人流术后恶心呕吐临床观察

目的 观察阿扎司琼联合小剂量地塞米松预防无痛人流术后恶心、呕吐的作用.方法 选择ASA Ⅰ一Ⅱ级择期行无痛人流术患者270例,随机分为A、B、C 3组,每组90例;分别静脉注射生理盐水、阿扎司琼及阿扎司琼+地塞米松,3组患者均注射丙泊酚(3 mg/kg)及芬太尼(0.6μg/kg),手术24 h后电话询问恶心、呕吐发生...

Clinical observation of combined Azasetron and low-dose dexamethasone for preventing postoperative nausea and vomiting in patients undergoing painless abortion surgery

Objective To observe the antiemetic effect of azasetron plus low-dose dexamethasone in patients undergoing painless abortion surgery.Methods 270 ASA physical status Ⅰ～Ⅱpatients scheduled for elective painless abortion surgery were randomly divided into 3 equal groups.Patients intravenously received saline(group A),azasetron(group B),azasetron plus low-dose dexamethasone(group C)respectively.Anesthesia was induced with propofol(3 mg/kg)in combination with fentanyl(0.6μg/kg).Patients were interviewed after 24 hours of the surgery by telephone.The incidence of postoperative nausea and vomiting was recorded.Results The overall incidence of POVA in group B and C were significantly lower than group A.There was no significant difference between group B and C.Conclusion Azasetron in combination with low-dose dexamethasone produced same antiemetic effect as azasetron alone in patients underwent painless abortion surgery.