Sagliker综合征颌面软硬组织的形态变化

目的 探索慢性肾功能衰竭晚期并发Sagliker综合征患者软、硬组织形态特点.方法 选择16例经肾内科转诊确诊为继发性甲状旁腺功能亢进的患者,分为两组：一组为继发性甲状旁腺功能亢进伴发Sagliker综合征组（SS组）,另一组为单纯甲状旁腺功能亢进组（SHPT组）,另常规拍摄头颅侧位片.结果 硬组织测量结果：两组∠SNA、∠ANB、颌突角（∠NA/PA）、下颌平面角∠MP/SN、∠MP/FH、∠SArGo和∠ArGoGn比较,差异有统计学意义（P＜0.05）,SS组明显大于SHPT组;软组织测量结果：两组颏唇角（∠LL-Bs-Pos）、上唇凸角（∠AsUL-FH）、上唇突距（UL-EP）、上下唇交角（∠AsUL-BsUL）比较,差异有统计学意义（P＜0.05）,SS组明显大于SHPT组;两组下唇凸角（∠BsLL-FH）比较,差异有统计学意义（P＜0.05）,SS组明显小于SHPT组.结论 Sagliker综合征患者软、硬组织发生特异性变化.

Morphological changes of craniofacial hard and soft tissues in Sagliker syndrome

Objective To investigate the craniofacial morphologies of Sagliker syndrome.Methods Sixteen patients were selected in this study that was diagnosed by the Department of Nephrology and the Center of Dentistry of China-Japan Friendship Hospital.They were divided into 2 groups：Sagliker syndrome group（SS） including 8 patients,and secondary hyperparathyroidism group （SHPT） including 8 patients.Cephalometric radiographs were taken from all the 16 patients.Results The hard issue measurement results had shown that in ∠SNA,∠ANB,∠NA/PA,∠MP/SN,∠MP/ FH,∠SArGo,and ∠ArGoGn,there were significantly statistical differences between the two groups.The measurements of SS were greater than that of SHPT.The soft issue measurement results had shown that in ∠LL-Bs-Pos,∠AsUL-FH,UL-EP,and ∠AsUL-BsUL,there were also significant differences between the two groups.The measurements of SS were greater than that of SHPT.In ∠BsLL-FH,there were evidently statistical differences between the two groups：the measurements of SS were greater than that of SHPT.Conclusions The facial hard and soft tissue of the patients with Sagliker syndrome have the special changes in morphologies.