剖宫产术预防性应用抗生素436例临床分析

目的 探讨剖宫产围手术期预防性应用抗生素的用药方案.方法 收治行剖宫产分娩产妇436例,回顾性分析剖宫产围手术期抗生素的不同用药方案.根据抗生素使用情况分为两组,观察组221例,剖宫产术中断脐后开始给药,术后继续使用1d;对照组215例,手术结束后开始给药,共5d.抗生素应用头抱呋辛钠,均为静脉给药.比较两组产妇术后感染、术后病率、术后体温恢复正常的时间及手术后住院天数.结果 两组在术后感染、术后病率方面差异无统计学意义（P＞0.05）,观察组术后体温恢复正常的时间、术后平均住院天数短于对照组,差异有统计学意义（P＜0.05）.结论 对剖宫产术中用药,术后预防性应用抗生素1d即能达到预防感染的目的,术后过长时间预防性使用抗生素并不增加预防术后感染的效果.

Clinical Analysis of 436 Cases on the Optimum Scheme Used Antibiotics of Cesarean Puerperal Preoperative Prophylactic

Objective To explore the optimum scheme used antibiotics of cesarean puerperal preoperative prophylactic.Method 436 cases of pregnant women with puerperal of cesarean parturition in Department of Obstetrics in our hospital from July 2012 to January 2013, antibiotics different therapeutic schemes of cesarean puerperal preoperative were retrospectively analyzed. They were divided into two groups,221 casesof the observation group,after umbilical cord was cut began to medicine,and postoperative continue to use 1 d;215 cases of the control group,began to medicine after the operation,5 d in all. cefuroxime sodium as antibiotics were given intravenously,Postoperative infection, postoperative morbidity, postoperative temperature returned to normal time and hospitalization daysof two groupswere compared.Result Postoperative infection and the postoperative morbidity they were no significant differences（P〈0.05）. Postoperative temperature returned to normal time, postoperative hospitalization days of the observation group were shorter than the control group, the differences were statistically significant（P〈0.05）.Conclusion women with puerperal of cesarean parturition, use once Antibiotic in the operation, postoperative prophylactic application of antibiotics in 1 days to reach the purpose of preventing infection, after long use of prophylactic antibiotics for prevention of postoperative infection dose not increase effect.