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Inhaled nitric oxide therapy in neonates and children: reaching a European consensus |
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| Authors: | Duncan J. Macrae David Field Jean-Christophe Mercier Jens Møller Tom Stiris Paolo Biban Paul Cornick Allan Goldman Sylvia Göthberg Lars E. Gustafsson Jürg Hammer Per-Arne Lönnqvist Manuel Sanchez-Luna Gunnar Sedin Nim Subhedar |
| Affiliation: | (1) Royal Brompton Hospital, Sydney Street, SW3 6NP London, U.K.;(2) Department of Child Health, Leicester Royal Infirmary, LE1 5WW Leicester, U.K.;(3) Hôpital Robert Debré, 48 Boulevard Sérurier, 75935 Paris Cedex 19, France;(4) Klinikum Saarbrucken, Winterberg 1, 66119 Saarbrucken, Germany;(5) Barn. Afd, Ullevål sykehus, 0407, Norway;(6) Neonatal and Paediatric Intensive Care Unit, Major City Hospital, Piazzale Stefania, 37126 Verona, Italy;(7) Great Ormond Street Children!["rsquo"]("/content/gr4kluhw0mmlm30m/xlarge8217.gif") s Hospital, Great Ormond Street, WC1 N 3JH London, U.K.;(8) Drottning Silvias Barnsjukhus, Sahlgrenska University Hospital, 41685 Gothenburg, Sweden;(9) Department of Physiology and Pharmacology, Karolinska Institutet, 17177 Stockholm, Sweden;(10) Kinderspital, Roemerstrasse 8, 4005 Basel, Switzerland;(11) Department of Paediatric Anaesthesia and Intensive Care, Astrid Lindgren Childrens Hospital, Karolinska Institutet, 17176 Stockholm , Sweden;(12) Servicio de Neonatologia, Hospital General Universitario Gregorio Maranon, Dr. Esquerdo 46, 28009 Madrid , Spain;(13) Akademiska sjukhuset, 75185 Uppsala, Sweden;(14) Neonatal Unit, Liverpool Womens Hospital, Crown Street, L8 7SS Liverpool, U.K. |
| Abstract: | Inhaled nitric oxide (iNO) was first used in neonatal practice in 1992 and has subsequently been used extensively in the management of neonates and children with cardiorespiratory failure. This paper assesses evidence for the use of iNO in this population as presented to a consensus meeting jointly organised by the European Society of Paediatric and Neonatal Intensive Care, the European Society of Paediatric Research and the European Society of Neonatology. Consensus Guidelines on the Use of iNO in Neonates and Children were produced following discussion of the evidence at the consensus meeting.Electronic Supplementary Material Supplementary material is available in the online version of this article at . |
| Keywords: | Inhaled nitric oxide Pulmonary hypertension Persistent pulmonary hypertension of the newborn Extracorporeal membrane oxygenation Vasodilator Pulmonary |
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