Suppressive effect of immature erythroid cells on the B-cell proliferation |
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| Authors: | D M Samarin G V Seledtsova V I Seledtsov V Ya Taraban V A Kozlov |
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| Institution: | (1) Institute of Clinical Immunology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk |
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| Abstract: | Immature erythroid cells suppress the proliferative response of preactivated B lymphocytes to lipopolysaccharide. The same
effect is observed when recombinant human interleukin-2 or culture medium conditioned by preactivated T or B cells is added
to cultured cells. Suppressive nucleate erythroid cells are resistant to leucine methyl ester.
Translated fromByulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 123, No. 1, pp. 66–70, January, 1997 |
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| Keywords: | erythroblast natural immunosuppression B-cell proliferation |
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