我院236例药品不良反应报告分析

目的:方法:了解我院药品不良反应(ADR)发生的特点。方法:对我院2005年8月1日~2005年12月31日收集的236例ADR报告分别从药品种类、年龄分布、给药途径、涉及器官或系统及临床表现等方面进行统计、分析。结果:236例ADR报告中,涉及药物以抗感染药居多(占38.98%),≥60a的患者ADR发生率最高(占30.51%),静脉给药方式是引发ADR的重要给药途径(占70.76%),ADR最为常见的临床表现为皮肤及附件损害(占36.86%)。结论:应合理使用抗感染药,避免或减少ADR的发生。

ADR Reports:Analysis of 236 Cases in Our Hospital

OBJECTIVE:To study the characteristics of adverse drug reactions(ADR) in our hospital.METHDOS:236 ADR cases collected from Aug.1,2005 to Dec.31,2005 in our hospital were analyzed statistically in respect of drug categories,age distribution,routes of administration,organs and systems involved and clinical manifestations.RESULTS:Of the 236 ADR cases,38.98% were induced by anti-infective drugs,30.51% occurred in patients aged ≥60a,70.76% were induced through intravenous way,and damages of skin and its appendants were the most common manifestations(36.86%).CONCLUSION:Anti-infective drugs should be used rationally to avoid or reduce the occurrence of ADR.