麋鹿角中多糖类成分资源化学分析评价

目的:分析与评价麋鹿角中多糖类成分。方法:分别采用Elson-Morgan法、硫酸咔唑法及苯酚硫酸法,以氨基葡萄糖、葡萄糖醛酸和葡萄糖为对照品,测定不同鹿龄及不同角部位麋鹿角样品中的氨基多糖、酸性多糖及中性多糖,并与鹿角进行比较。结果:多糖类成分含量因鹿龄和角部位不同存在较大差异。3种多糖类成分总含量以2岁龄麋鹿角为最高,其次为5岁龄,6~8岁龄,3岁龄和4岁龄。不同鹿龄麋鹿角3个角部位平均含量均以中性多糖为最高,其次是氨基多糖,酸性多糖含量相对较低。3种多糖在3个角部位中的平均含量均以2岁龄麋鹿角为最高,其中氨基多糖和中性多糖的含量与宁夏产鹿角接近,酸性多糖低于宁夏产鹿角。结论:该研究可为麋鹿角药用资源的合理利用及其产业化提供科学依据。

Resource Chemistry Evaluation of Saccharides in Elaphuri Davidiani Cornu and Cervi Cornu

Objective: To analyze and evaluate polysaccharides in Elaphuri Davidiani Cornu(EDC) and Cervi Cornu(CC). Method: Glycosaminoglycan, neutral and acidic polysaccharides in EDC and CC were determined and compared by using Elson-Morgan, sulfuric acid carbazole colorimetry and phenol-sulphate acid method, with glucosamine, glucuronic acid and glucose as control drugs. Result: The contents of the three polysaccharides from different ages or sections of samples varied obviously. The highest total content of the three polysaccharides was found in 2-year-old EDC, which was followed by 5, 6-8, 3 and 4-year-old samples. The highest average content of three polysaccharides in the three sections were found in 2-year-old EDC, and the glycosaminoglycan and neutral polysaccharides contents were close to that in CC, but the acidic polysaccharides content was lower than CC. The neutral polysaccharides were the highest in all the EDC samples of various ages, which was followed by glycosaminoglycan and acidic polysaccharides. Conclusion: The study can provide a scientific basis for rational utilization of EDC resources of and its industrialization.