Affiliation: | (1) Division of Gastroenterology, Institute of Internal Medicine, Norway;(2) Department of Clinical Nutrition, Norway;(3) Laboratory for Clinical Biochemistry/Centre for Occupational and Environmental Allergy, Haukeland University Hospital, Norway;(4) National Institute of Nutrition and Seafood Research, Norway;(5) Department of Biological and Medical Psychology, University of Bergen, Norway;(6) Department of Psychiatry, Haukeland University Hospital/University of Bergen, Bergen, Norway;(7) Institute of Medicine, Haukeland University Hospital, N-5021 Bergen, Norway |
Abstract: | Perceived food hypersensitivity is much more common than food allergy as medically verified. Unexplained symptoms and wrong attribution are typical in subjective health complaints. We hypothesize that subjective health complaints and worries are abnormally prevalent among patients with subjective food hypersensitivity. Forty-six patients with subjective food hypersensitivity and two control groups, one formed by 50 health care workers and one by 70 sex- and age-matched volunteers from the general population, were included in our study. All filled in two questionnaires: Subjective Health Complaints Inventory and Modern Health Worries Scale. None of the patients had IgE-mediated food allergy. The patients scored significantly higher than the controls on sum scores for four domains of subjective health complaints, including gastrointestinal complaints (P < 0.001), musculoskeletal complaints (P < 0.01), “pseudoneurology” (P < 0.001), and allergy (P < 0.001). Sum scores on modern health worries did not differ significantly between groups. The results support our hypothesis of an association between subjective food hypersensitivity and subjective health complaints, corroborating the view that, in the absence of food allergy, the conditions are sharing pathogenetic mechanisms. |