Neurotensin: an endogenous antipsychotic? |
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| Authors: | Becky Kinkead Charles B Nemeroff |
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| Affiliation: | Laboratory of Neuropsychopharmacology, Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Suite 4000 Woodruff Memorial Research Building, 1639 Pierce Drive, Atlanta, Georgia 30322, USA. |
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| Abstract: | Despite evidence from a variety of experimental approaches implicating the neuropeptide neurotensin in both the mechanism of action of antipsychotic drugs and the pathophysiology of schizophrenia, there has been some debate as to whether a peripherally administered neurotensin receptor agonist represents a sound strategy for the development of a novel class of antipsychotic drugs. |
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