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A case of large cell CNS lymphoma associated with a systemic small cell lymphocytic lymphoma |
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| Authors: | David E Weissman Brian D Kueck Ann B Merkow |
| Institution: | (1) The Division of Hematology/Oncology, Department of Medicine and the Department of Pathology, The Medical College of Wisconsin, Milwaukee, Wisconsin, USA;(2) Milwaukee County Medical Complex, 8700 W. Wisconsin Ave, 53226 Milwaukee, WI, USA |
| Abstract: | Summary A case is reported of a 59 y/o woman with a large cell CNS lymphoma and a small cell lymphocytic lymphoma in the bone marrow. The brain tumor underwent spontaneous regression and subsequent regrowth while there was slow progression of the systemic small cell lymphoma. The CNS lymphoma regressed rapidly following treatment with prednisone and cyclophosphamide. We hypothesize that the small cell lymphoma in this patient may represent an underlying immunodeficiency disorder. Dr. Weissman is a recipient of an American Cancer Society Career Development Award. |
| Keywords: | malignant lymphoma non-hodgkin's lymphoma central nervous system lymphoma immunodeficiency |
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