| 线粒体DNA的损伤及其对细胞的影响 |
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| 引用本文： | 唐春,别平,TANG Chun,BIE Ping. 线粒体DNA的损伤及其对细胞的影响[J]. 第二军医大学学报, 2006, 27(2): 211-214 |
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| 作者姓名： | 唐春 别平 TANG Chun BIE Ping |
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| 作者单位： | 第三军医大学西南医院全军肝胆外科研究所,重庆,400038;第三军医大学西南医院全军肝胆外科研究所,重庆,400038 |
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| 摘 要： | 线粒体DNA(Mitochondrial DNA,mtDNA)是线粒体内具有遗传效应的双股闭环DNA分子,其遗传信息量虽小,却控制着线粒体一些最基本的性质,对细胞及其功能有着重要影响.mtDNA的损伤会导致细胞结构及功能的变化,已越来越引起人们的重视.本文就近年来mtDNA的损伤及其对细胞影响的研究进展作一综述.
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| 关 键 词： | DNA 线粒体 DNA损伤 细胞 |
| 文章编号： | 0258-879X（2006）02-0211-04 |
| 收稿时间： | 2005-06-13 |
| 修稿时间： | 2005-12-15 |
Damage of mitochondrial DNA and its influence on cells |
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| TANG Chun,BIE Ping. Damage of mitochondrial DNA and its influence on cells[J]. Former Academic Journal of Second Military Medical University, 2006, 27(2): 211-214 |
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| Authors: | TANG Chun BIE Ping |
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| Abstract: | Mitochondrial DNA(mtDNA),a double-stranded circular molecular,encodes several genes essential for mitochondrial and cellular functions despite its small amount of genetic information.Damage of mtDNA can lead to changes of cellular structures and functions and this fact is drawing more and more attention.This review summarized the recent research about mtDNA damage and its influence on cells. |
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| Keywords: | DNA,mitochondrial DNA damage cells |
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