Use of Human Intestinal Enteroids to Evaluate Persistence of Infectious Human Norovirus in Seawater |
| |
| Authors: | Marion Desdouits,David Polo,Cecile Le Mennec,Sofia Strubbia,Xi-Lei Zeng,Khalil Ettayebi,Robert L. Atmar,Mary K. Estes,Franç oise S. Le Guyader |
| |
| Affiliation: | Institut Franҫais de Recherche pour l’Exploitation de la Mer, Nantes, France (M. Desdouits, D. Polo, C. Le Mennec, S. Strubbia, F.S. Le Guyader);Baylor College of Medicine, Houston, Texas, USA (X.-L. Zeng, K. Ettayebi, R.L. Atmar, M.K. Estes) |
| |
| Abstract: | Little data on the persistence of human norovirus infectivity are available to predict its transmissibility. Using human intestinal enteroids, we demonstrate that 2 human norovirus strains can remain infectious for several weeks in seawater. Such experiments can improve understanding of factors associated with norovirus survival in coastal waters and shellfish. |
| |
| Keywords: | Norovirus persistence stability human intestinal enteroids marine environment viruses enteric infections food safety France United States |
|
|
