呋塞米雾化治疗AECOPD的临床观察

目的:探讨呋塞米雾化吸入治疗慢性阻塞性肺疾病急性期(AECOPD)的临床疗效。方法:将在57例AECOPD患者随机分两组,试验组29例,对照组28例,在常规治疗基础上试验组给呋塞米40 mg加0.9%NaCl溶液20 ml,对照组给庆大8万U加地塞米松5 mg加α-糜蛋白酶4 000μ加0.9%NaCl溶液15 ml,雾化吸入2次/d,7 d后观察治疗效果。结果:试验组总有效率为90%优于对照组64%,两组比较差异有统计学意义(P<0.05)。结论:呋塞米雾化吸入治疗AECOPD效果满意,安全、便捷、价廉适合临床推广。

Clinical observation of furosemide aerosol treatment of AECOPD

Objective To study the furosemide aerosol clinical curative effect of chronic obstructive pulmonary disease(AECOPD) in the acute phase.Method 57 patients in our hospital were randomly divided into two groups,29 cases in experimental group,28 cases in control group.Except the conventional treatment,the experimental group also had furosemide 40 mg + saline 20 ml and the control group had gentamicin 80000 +dexamethasone 5 mg +chymotrypsin 4000 μ + saline 15 ml.Curative effect was observed after 7 days with atomization inhalation twice a day.Results The total effective rate in the experimental group was 89.65% which is better than the control group with the rate of 64.29%.The results had statistically significant difference(P<0.05).Conclusion Furosemide atomization inhalation in the treatment of AECOPD is safe,convenient and inexpensive with satisfactory effect,which is worth clinical promotion.