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巴氏涂片与液基细胞学宫颈检查结果分析
引用本文:陈颂平,赵丽琴,李洪钧.巴氏涂片与液基细胞学宫颈检查结果分析[J].西部医学,2014(5):551-552,555.
作者姓名:陈颂平  赵丽琴  李洪钧
作者单位:南方医科大学第三附属医院,广东广州510000
摘    要:目的 分析巴氏涂片和液基细胞学(TCT)宫颈检查结果,为宫颈液基细胞学检查的临床应用提供理论依据.方法 选取在我院体检中心妇科接受宫颈细胞学筛查的患者3800例.将接受巴氏涂片检查的1900例患者分为A组,接受液基细胞学检查的1900例患者分为B组,对比巴氏涂片和液基细胞学检查的阳性率,同时以阴道镜活检结果为金标准,对比两组检查的符合率.结果 A组的阳性率为6.89%,ASCUS检出率为5.05%,LSIL检出率为1.42%,HSIL检出率为0.26%;B组的阳性率为14.16%,ASCUS检出率为8.26%,LSIL检出率为4.84%,HSIL检出率为0.79%.A组的阳性率、ASCUS检出率、LSIL检出率、HSIL检出率均显著低于B组(均P<0.05);和阴道镜活检结果对比,A组LSIL患者的诊断符合率为62.96%,B组LSIL患者的诊断符合率为85.87%.A组LSIL的诊断符合率均显著低于B组(P<0.05).结论 液基细胞学检查能够显著提高宫颈病变的阳性率,减少假阴性结果,且诊断结果和病理诊断的符合率高,更适合于宫颈病变的筛查.

关 键 词:巴氏涂片  液基细胞学  阴道镜活检  宫颈检查

Analysis of Pap smear and liquid based cytology on examination of cervical
CHENG Song-ping,ZHAO Li-qin,LI Hong-jun.Analysis of Pap smear and liquid based cytology on examination of cervical[J].Medical Journal of West China,2014(5):551-552,555.
Authors:CHENG Song-ping  ZHAO Li-qin  LI Hong-jun
Institution:(The Third Affiliated Hospital of Southern Medical University, Guangzhou 510000)
Abstract:Objective To analyze Pap smear and liquid based cytology (TCT) cervical examination results and provide a theoretical basis for the clinical application of liquid based cervical cytology.Methods 3800 patients were divided into A group and B group.A group was treated with Papanicolaou smears and B group with liquid based cytology.The results of Papanicolaou smears and liquid based cytology were compared with colposcopy biopsy.Results The positive rate of A group was 6.89%.ASCUS positive rate was 5.05%.LSIL positive rate was 1.42%.HSIL positive rate was 0.26%.The positive rate of B group was 14.16%,ASCUS positive rate was 8.26%,LSIL positive rate was 4.84%,the detection rate of HSIL was 0.79%.The rate of ASCUS and the detection rate of LSIL and HSIL of the A group were significantly lower than that of B group (P<0.05).Contrasted with colposcopy biopsy,coincidence rate of A group and B group were 62.96% and 85.87%.Conclusion Liquid based cytology can significantly improve the positive rate of cervical lesions,reduce the false negative results.
Keywords:Pap smear  Liquid based cytology  Cervical biopsy  Colposcopy examination
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