Nutritional screening in a cancer prehabilitation programme: A cohort study |
| |
| Authors: | Sorrel T. Burden Neil Bibby Kirsty Donald Kellie Owen Kirsty Rowlinson-Groves Chloe French Loraine Gillespie Jack Murphy Sarah Jayne Hurst Robert Mentha Karly Baguley Ash Rowlands Karen McEwan Zoe Merchant John Moore |
| |
| Affiliation: | 1. School of Health Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK;2. Manchester Royal Infirmary, Oxford Road, Manchester, UK;3. Salford Royal Hospital, Northern Care Alliance Foundation Trust, Scott Lane, Salford, UK;4. Prehab4Cancer GM Cancer Alliance, Christie NHS Foundation trust, Greater Manchester, UK;5. The Christie NHS Foundation Trust, Wilmslow Road, Manchester, UK;6. Primary Care Lead for GM Cancer Prehab4Cancer, UK |
| |
| Abstract: | Background Cancer patients are often malnourished pre-operatively. The present study aimed to establish whether current screening was appropriate for use in prehabilitation and investigate any association between nutritional risk, functionality and quality of life (QoL). Methods This cohort study used routinely collected data from September 2020 to August 2021 from patients in a Prehab4cancer programme. Included patients were aged ≥ 18 years, had colorectal, lung or oesophago-gastric cancer and were scheduled for surgery. Nutritional assessment included Patient-Generated Subjective Global Assessment (PG-SGA) Short-Form and QoL with a sit-to-stand test. Association between nutritional risk and outcomes was analysed using adjusted logistic regression. Results From 928 patients referred to Prehab4Cancer service over 12 months, data on nutritional risk were collected from 526 patients. Pre-operatively, 233 out of 526 (44%) patients were at nutritional risk (score ≥ 2). During prehabilitation, 31% of patients improved their PG-SGA and 74% of patients maintained or improved their weight. Odds ratios (OR) with confidence intervals (CI) showed that patients with better QoL using EuroQol-5 Dimensions (OR = 0.05, 95% CI = 0.01, 0.45, p = 0.01), EuroQol Visual Analogue Scale (OR = 0.96, 95% CI = 0.93, 1.00, p = 0.04) or sit-to-stand (OR = 0.96, 95% 0.93, 1.00, p = 0.04) were less likely to be nutritional at risk. Conclusions Almost half of patients in Prehab4Cancer programme assessed using PG-SGA were at risk of malnutrition. However, almost half of the sample did not have their risk assessed. Patients at risk of malnutrition were more likely to have a poorer QoL and sit-to-stand test than those who were not at risk. |
| |
| Keywords: | cancer cellular and physiological function disease/therapeutic areas malnutrition quality of life |
|
|
