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肾上腺意外瘤中醛固酮瘤患者左心室肥厚改变的研究
引用本文:张煜,刘建彬,黄知敏,邓婉萍,赵晓娟,伍基颜,李延兵.肾上腺意外瘤中醛固酮瘤患者左心室肥厚改变的研究[J].湖南师范大学学报(医学版),2013,0(2):55-57.
作者姓名:张煜  刘建彬  黄知敏  邓婉萍  赵晓娟  伍基颜  李延兵
作者单位:张煜 (广东医学院附属东莞市厚街医院,广东 东莞,523945); 刘建彬 (中山大学附属第一医院内分泌科,广东 广州,510080); 黄知敏 (中山大学附属第一医院内分泌科,广东 广州,510080); 邓婉萍 (中山大学附属第一医院内分泌科,广东 广州,510080); 赵晓娟 (中山大学附属第一医院内分泌科,广东 广州,510080); 伍基颜 (中山大学附属第一医院内分泌科,广东 广州,510080); 李延兵 (中山大学附属第一医院内分泌科,广东 广州,510080);
基金项目:广东省科技计划项目(项目编号:012B031800271)
摘    要:目的:探讨肾上腺意外瘤中醛固酮瘤的左心室肥厚情况。方法:肾上腺意外瘤中醛固酮瘤患者21例(A组)和有症状的醛固酮瘤患者30例(B组),分别记录一般临床资料和生化指标,并进行超声心动图检查。对两组患者的临床特征、生化检测结果和左心室肥厚程度进行比较分析。结果:(1)B组左室后壁厚度、LVM、LVMI高于A组。(2)醛固酮瘤患者LVMI与立位血浆醛固酮独立相关。(3)B组左室肥厚发生率高于A组。结论:肾上腺意外瘤中醛固酮瘤的醛固酮分泌轻度升高可导致左心室肥厚。

关 键 词:醛固酮瘤  肾上腺意外瘤  左室肥厚  左室质量  左室质量指数

The study of left ventricular hypertrophy in patients with aldosteronoma in adrenal incidentaloma
Zhang Yu,Liu Jianbin,Huang Zhimin,Deng Wanping,Zhao Xiaojuan,Wu Jiyan,Li Yanbing.The study of left ventricular hypertrophy in patients with aldosteronoma in adrenal incidentaloma[J].Journal of Hunan Normal University(Medical Science),2013,0(2):55-57.
Authors:Zhang Yu  Liu Jianbin  Huang Zhimin  Deng Wanping  Zhao Xiaojuan  Wu Jiyan  Li Yanbing
Institution:1.Endocrinology Department,Houjie Hospital of Guangdong Medical College,Dongguan 523945,China;2.Endocrinology Department,the First Affiliated Hospital of Sun Yat-sen University,Guangzhou,510080,China)
Abstract:Objective To investigate the left ventricular hypertrophy in patients with aldosteronoma in adrenal incidentaloma.Methods 21 patients with aldosteronoma in adrenal incidentaloma(group A) were evaluated,all of whom were recorded clinical data,biochemical indicators,and examined by echocardiography.These data were compared with those of 30 typical aldosteronoma(group B).Results ⑴ Group B patients had significant greater left ventricular posterior wall thickness(PWd),LVM,LVMI compared with group A patients.⑵Multiple regression analysis showed a correlation between LVMI and upright plasma aldosterone in aldosteronoma(P<0.05).3)the incidence of left ventricular hypertrophy in group 2 was higher than in group 1(P<0.05).Conclusion aldosteronoma in adrenal incidentaloma,whose aldosterone secretion mild elevated could lead to left ventricular hypertrophy.
Keywords:aldosteronoma  adrenal incidentaloma  left ventricular hypertrophy  left ventricular mass  left ventricular mass index
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