NT-proBNP评估非肥胖ACS患者PCI术预后

目的:探讨N端脑钠肽前体(NT-proBNP)对非肥胖急性冠状动脉综合征(ACS)经皮冠脉介入(PCI)术后主要不良心脏事件(MACE)的预测价值。方法 :因ACS行PCI手术的非肥胖患者101例,分为低NT-proBNP水平组(NT-proBNP≤80 pg/ml)31例,高NT-proBNP水平(NT-proBNP>80 pg/ml)组70例,统计并分析患者PCI术后6个月内MACE发生率。结果:高NT-proBNP水平组PCI术后MACE发生率高于低NT-proBNP水平组;NT-proBNP可独立预测非肥胖ACS患者PCI术后MACE发生率、死亡率、和心衰的发生率。结论:血浆NT-proBNP水平可用于评估非肥胖ACS患者冠脉病变的范围PCI术后短期(6个月内)的预后。

The estimate of prognosis in ACS patients of unobese after PCI by NT-proBNP level

Objective To investigate the clinical prognostic value of major abnormal cardiacevents(MACE) in unobese patients of acute coronary syndrome(ACS) patients before percutaneous coronary intervention(PCI)by plasma N-terminal pro-B-type natriuretic peptide(NT-proBNP).Methods A total of 101 unobese patients of acute coronary syndrome,which were divided into ≤80pg/ml group of 31 patients and 〉80pg/ml group of 70 patients.follow-up major abnormal cardiac events(including death,cardiogenic shock,recurrent angina pectoris,non-fatal re-infarction,non-fatal heart failure,arrhythmia,target vessel revascularization,re-admitted to hospital composite end point) within 6 months after PCI.Results 1.In un-obese patients,MACE、death and CHF times of patients with NT-proBNP>80pg /ml were significantly higher than these times of patients with NT-proBNP≤ 80 pg/ml(P< 0.05);2.in patients unobese,NT-proBNP levels predicted MACE、death and CHFwas significant(P<0.001),Conclusion This clinical study results show that NT-proBNP can predicted MACE、death and CHF in unobese patients within 6 moths after PCI.