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Evaluation of NGS and RT-PCR Methods for ALK Rearrangement in European NSCLC Patients: Results from the European Thoracic Oncology Platform Lungscape Project
Authors:Igor Letovanec  Stephen Finn  Panagiota Zygoura  Paul Smyth  Alex Soltermann  Lukas Bubendorf  Ernst-Jan Speel  Antonio Marchetti  Daisuke Nonaka  Kim Monkhorst  Henrik Hager  Miguel Martorell  Aleksandra Sejda  Richard Cheney  Javier Hernandez-Losa  Eric Verbeken  Walter Weder  Spasenija Savic  Arne Warth
Affiliation:1. Institute of Pathology, Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, Switzerland;2. Department of Histopathology, St James''s Hospital and Trinity College, Dublin, Ireland;3. Frontier Science Foundation-Hellas, Athens, Greece;4. Institute of Pathology and Molecular Pathology, University Hospital Zürich, Zürich, Switzerland;5. Institute of Pathology, University Hospital Basel, Basel, Switzerland;6. Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands;g. Center of Predicitve Molecular Medicine, CeSI, University of Chieti-Pescara, Chieti, Italy;h. Department of Histopathology, The Christie National Health Service Foundation Trust, Manchester, United Kingdom;i. Division of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands;j. Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark;k. Department of Pathology, Consorcio Hospital General Universitario de Valencia, Valencia, Spain;l. Department of Pathomorphology, Medical University of Gdansk, Gdansk, Poland;m. Department of Pathology, State University of New York at Buffalo, Buffalo, New York;n. Department of Pathology, Vall d''Hebron University Hospital, Barcelona, Spain;o. Department of Pathology, University Hospital KU Leuven, Leuven, Belgium;p. Department of Thoracic Surgery, University Hospital Zürich, Zürich, Switzerland;q. Medical Oncology Department, Vall d’Hebrone University Hospital, Barcelona, Spain;r. Department of Pathology, Heidelberg University Hospital, Heidelberg, Germany;s. Department of Thoracic Oncology, The Netherlands Cancer Institute-Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands;t. Department of Oncology, Aarhus University Hospital, Aarhus, Denmark;u. Deparment of Medical Oncology, The Chrisite NHS Foundation Trust, Manchester, United Kingdom;v. Department of Pulmonology, Maastricht University Medical Center, Maastricht, The Netherlands;w. Department of Surgery, Thoraxklinik at Heidelberg University, Heidelberg, Germany;x. Department of Oncology and Radiotherapy, Medical University of Gdansk, Poland;y. Department of Respiratory Oncology, University Hospital KU Leuven, Leuven, Belgium;z. European Thoracic Oncology Platform, Bern, Switzerland;11. Thermo Fisher Scientific, Paisley, United Kingdom;22. Thermo Fisher Scientific, Austin, Texas;33. Frontier Science Foundation-Hellas & University of Athens, Athens, Greece;44. Department of Pathology, Aberdeen Royal Infirmary, Aberdeen, United Kingdom;55. Department of Pathology, VU University Medical Center, Amsterdam, The Netherlands;66. Clinic of Oncology, University Hospital Zürich, Zürich, Switzerland;gg. Department of Oncology, Centre Hospitalier Universitaire Vaudois CHUV, Lausanne, Switzerland
Abstract:
Keywords:NSCLC  ALK  NGS  RT-PCR
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